期刊
ENVIRONMENTAL POLLUTION
卷 157, 期 4, 页码 1127-1133出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2008.10.002
关键词
Redox; Metallic; Nanoparticles; Toxicity; Oxidative stress
资金
- French National Program ACI-FNS (ANR)
- INSU
- US National Science Foundation
- Direct For Biological Sciences
- Div Of Biological Infrastructure [830093] Funding Source: National Science Foundation
The level of production of nanoparticles will inevitably lead to their appearance in air, water, soils, and organisms. A theoretical framework that relates properties of nanoparticles to their biological effects is needed to identify possible risks to human health and the environment. This paper considers the properties of dispersed metallic nanoparticles and highlights the relationship between the chemical stability of these nanoparticles and their in vitro toxicity. Analysis of published data suggests that chemically stable metallic nanoparticles have no significant cellular toxicity, whereas nanoparticles able to be oxidized, reduced or dissolved are cytotoxic and even genotoxic for cellular organisms. (C) 2008 Elsevier Ltd. All rights reserved.
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