期刊
ENVIRONMENTAL MICROBIOLOGY
卷 14, 期 8, 页码 1817-1829出版社
WILEY
DOI: 10.1111/j.1462-2920.2011.02617.x
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资金
- European Commission
- Swedish Research Council Natural Sciences
- Petrus and Augusta Hedlund Foundation
- Carl Trygger Foundation
- Karolinska Institutet
The secondary messenger cyclic di-GMP coordinately regulates the transition between motility/sessility/virulence in bacterial populations and upon adaptation to novel habitats. Thereby, multiple independent regulatory circuits regulate a diversity of targets. This specific output response is surprising considering the diverse physiological processes regulated by this signalling molecule, which range from transcription to proteolysis and clearly demonstrates the presence of sophisticated developmental programmes in these so-called simple organisms.
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