期刊
ENVIRONMENT INTERNATIONAL
卷 68, 期 -, 页码 177-184出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2014.03.025
关键词
Pharmaceuticals; Exposure assessment; Mediterranean Sea; Mars 3D model; POCIS
资金
- French Agence Nationale de la Recherche (ANR)
- UM1 (University of Montpellier)
- VEOLIA ENVIRONNEMENT-HydroSciences: Risk analysis relating to emerging contaminants in water bodies
- Veolia Environnement Herault (France)
Concentrations of the antiepileptic drugs carbamazepine (Cbz), oxcarbazepine (OxCz) and their main metabolites were predicted in a wastewater treatment plant (WTP) and in the vicinity of its submarine outfall located in a Mediterranean coastal zone. Refined predicted environmental concentrations (PECs) were calculated in effluents based on consumption data and human excretion rates. PECs were estimated in the sea using the hydrodynamic MARS 3D model integrating meteorological data, oceanic conditions (wind, tide, atmospheric pressure), freshwater and sewage inputs. Measured environmental concentrations (MECs) were compared to PECs to assess the estimation relevance. In the coastal zone, PEC and MEC were in the same magnitude range. Modeling of Cbz diffusion and advection just above the submarine outfall showed the influence of the thermocline during summer, with low diffusion of Cbz from the bottom to the surface. This work allowed understanding the dispersion of target compounds and deserved further development for a better acknowledgement of vulnerability at local scales. (C) 2014 Elsevier Ltd. All rigths reserved.
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