期刊
ENVIRONMENT INTERNATIONAL
卷 35, 期 3, 页码 512-515出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2008.07.023
关键词
Arsenic; Selenium; Toxin; Micronutrients
资金
- United States Public Health Service [GM52216]
- American Heart Association Postdoctoral Fellowship [0520014Z]
Arsenic and selenium are metalloids found in the environment. Arsenic is considered to pose the most significant potential threat to human health based on frequency of occurrence. toxicity and human exposure. Selenium, on the other hand. ranks only 147th in toxicity but, in contrast to arsenic, is a required micronutrient. Whether a toxin or micronutrient, their metabolism requires that cells to accumulate these metalloids. In this review we discuss the membrane proteins that transport arsenic and selenium into cells, from bacteria to humans, as well as some of the efflux proteins involved in detoxification. (C) 2008 Elsevier Ltd. All rights reserved.
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