期刊
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
卷 19, 期 1-3, 页码 109-134出版社
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S1088424615300037
关键词
photodynamic therapy; nanoparticles; nanoplatforms; cancer-imaging; multimodality agents; theranostics; fluorescence; nuclear imaging; magnetic resonance imaging
资金
- NIH [CA119358, PO1 CA55791, RO1 CA127369, R21 CA176154]
- Photolitec, LLC, Roswell Park Alliance
- NCI Cancer Support Grant [CA016156]
This review article briefly describes: (a) the advantages in developing multifunctional nanoparticles for cancer-imaging and therapy, (b) the advantages and limitations of most of the porphyrin-based compounds in fluorescence imaging and photodynamic therapy (PDT), (c) problems associated with current Food and Drug Administration (FDA) approved photosensitizers, (d) challenges in developing in vivo target-specific PDT agents, (e) development of porphyrin-based nuclear-imaging agents (PET, SPECT) with an option of PDT, (f) the importance of light dosimetry in PDT, (g) the role of whole body or local hyperthermia in enhancing tumor-uptake, tumor-imaging and phototherapy and finally, (h) the advantages of photosensitizer-gold nanocages (Ps-Au NC) in photoacoustic and PDT.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据