期刊
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
卷 53, 期 9, 页码 1082-1093出版社
WILEY
DOI: 10.1002/pola.27539
关键词
amphiphilic; click chemistry; poly(ethylene glycol); polymers; silicone; surface chemistry; thermoset elastomers
资金
- Natural Sciences and Engineering Research Council of Canada
- 20/20 NSERC Ophthalmic Materials Network
- NSERC
- Alexander Graham Bell Canada Graduate Scholarship D Level
The hydrophobicity of silicone elastomers can compromise their utility in some biomaterials applications. Few effective processes exist to introduce hydrophilic groups onto a polysiloxane backbone and subsequently crosslink the material into elastomers. This problem can be overcome through the utilization of metal-free click reactions between azidoalkylsilicones and alkynyl-modified silicones and/or PEGs to both functionalize and crosslink silicone elastomers. Alkynyl-functional PEG was clicked onto a fraction of the available azido groups of a functional polysiloxane, yielding azido reactive PDMS-g-PEG rake surfactants. The reactive polymers were then used to crosslink alkynyl-terminated PDMS of different molecular weights. Using simple starting materials, this generic yet versatile method permits the preparation and characterization of a library of amphiphilic thermoset elastomers that vary in their composition, crosslink density, elasticity, hydrogel formation, and wettability. An appropriate balance of PEG length and crosslink density leads to a permanently highly wettable silicone elastomer that demonstrated very low levels of protein adsorption. (c) 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 1082-1093
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据