期刊
ENDOSCOPY
卷 42, 期 8, 页码 613-619出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1255514
关键词
-
资金
- E-Da hospital [EDAHP-98-016]
Background and study aim: Although narrow-band imaging (NBI) in endoscopy can improve detection of early-stage esophageal malignancies in patients with head and neck cancers, false-positive results may be obtained in areas with nonspecific inflammatory changes. This study evaluated the feasibility of primary screening with NBI and magnification for the presence of esophageal malignancies in these cancer patients. Patients and methods: Sixty-nine patients with documented head and neck cancers were enrolled from April 2008 to January 2009. All patients underwent a meticulous endoscopic examination of the esophagus using a conventional white-light system followed by re-examination using the NBI system and final confirmation with NBI plus magnification. Results: Twenty-one patients (30.4%) were confirmed to have esophageal neoplasia. Among these 21, 16 (76.2%) had synchronous lesions, 9 (42.9%) were asymptomatic, and 10 (47.6%) had early-stage neoplasia. The incidence of multiple esophageal neoplasia was 57.1%. NBI was more effective than conventional endoscopy in detecting neoplastic lesions (35 lesions in 21 patients vs. 22 lesions in 18 patients) and was particularly effective in patients with dysplasia (13 lesions in 9 patients vs. 3 lesions in 3 patients). The sensitivity and accuracy of detection were 62.9% and 64.4% for conventional endoscopy, 100% and 86.7% for NBI alone, and 100% and 95.6% for NBI with high magnification, respectively. Conclusions: Compared with current approaches, NBI followed by high magnification significantly increases the accuracy of detection of esophageal neoplasia in patients with head and neck cancers. The result warrants conducting prospective randomized controlled study to confirm its efficacy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据