4.3 Article

The Human Genome and Sport, Including Epigenetics, Gene Doping, and Athleticogenomics

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W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ecl.2009.10.010

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Athleticogenomics; Epigenetics; Gene doping; Genome sport

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Hugh Montgomery's discovery of the first of more than 239 fitness genes together with rapid advances in human gene therapy have created a prospect of using genes, genetic elements, and cells that have the capacity to enhance athletic performance (to paraphrase the World Anti-Doping Agency's definition of gene doping). This brief overview covers the main areas of interface between genetics and sport, attempts to provide a context against which gene doping may be viewed, and predicts a futuristic legitimate use of genomic (and possibly epigenetic) information in sport.

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