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Gijs van Haaften et al.
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Niamh H. Foley et al.
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C. Lu et al.
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J. J. Molenaar et al.
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Goleeta Alam et al.
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Niamh Lynam-Lennon et al.
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Brian J. Lestini et al.
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Kaiji Hu et al.
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Isabella Bray et al.
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Abraham Fong et al.
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S. Giordano et al.
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Andre Schrattenholz et al.
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Yael P. Mosse et al.
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Rani E. George et al.
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Nicole Tietze et al.
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J. S. Wei et al.
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J. Kang et al.
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Laura Fontana et al.
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Julie R. Park et al.
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Jan Stenvang et al.
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Thomas L. Sims et al.
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Geert J. Schenk et al.
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Dirk Geerts et al.
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Manabu Soda et al.
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C. Welch et al.
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Liang Zhang et al.
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Tsung-Cheng Chang et al.
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Pietro Laneve et al.
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Susan R. Rheingold et al.
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Sarah E. Furchert et al.
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Orly Reiner et al.
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B Tanno et al.
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S Oltra et al.
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C Bähr et al.
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J Kitlinska et al.
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X Zheng et al.
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RA Cairns et al.
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EJ Yeo et al.
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HA Burgess et al.
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SL Pomeroy et al.
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E Vreugdenhil et al.
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A Nakagawara
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HA Burgess et al.
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