期刊
ENDOCRINE PATHOLOGY
卷 25, 期 3, 页码 209-213出版社
HUMANA PRESS INC
DOI: 10.1007/s12022-013-9276-5
关键词
Pituitary; Neoplasia; Genomics; Epigenetics
The genetic mutations underlying familial syndromes that include pituitary tumors are rarely noted in the majority of sporadic adenohypophyseal adenomas. In contrast, epigenetic dysregulation is common, resulting in differential expression of cell cycle and apoptosis regulators, adhesion molecules, growth factors, and metabolic determinants of cell function. Here, we discuss the diagnostic and therapeutic implications of these findings as the landscape of pituitary tumor defects unfolds.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据