期刊
ENDOCRINE JOURNAL
卷 58, 期 7, 页码 607-611出版社
JAPAN ENDOCRINE SOC
DOI: 10.1507/endocrj.K11E-018
关键词
Hypoglycemia; Insulin overdose; Treatment; Japanese
Insulin overdose results in prolonged hypoglycemia. We hypothesized that if a huge amount of insulin is subcutaneously injected, the duration of hypoglycemia depends on the dose of insulin rather than the type of insulin. We conducted a literature review of insulin overdose and 33 cases were included in this study. We assessed the correlation between recovery time from hypoglycemia and insulin dose. As a result, there was a significant correlation between recovery time from hypoglycemia and insulin dose (r = 0.88, p < 0.0001) and this correlation was expressed as y = 0.045x; where y is time (h) and x is insulin dose (U), corresponding to that if 1000 U insulin is injected, hypoglycemia will persist for similar to 45 h. This equation may be useful to predict the duration of glucose supplementation for treatment of insulin overdose.
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