期刊
EMBO REPORTS
卷 15, 期 10, 页码 1023-1035出版社
WILEY
DOI: 10.15252/embr.201438993
关键词
aggression; decision-making; nutrient sensing; obesity; sexual behaviour
资金
- Rockefeller University
- Klarman Family Foundation Grants Program in Eating Disorders Research
- IMP
- Boehringer Ingelheim
- Human Frontier Science Program
- Gulbenkian Science Institute and FCT-Portugal
People think they are in control of their own decisions: what to eat or drink, whom to marry or pick a fight with, where to live, what to buy. Behavioural economists and neurophysiologists have long studied decision-making behaviours. However, these behaviours have only recently been studied through the light of molecular genetics. Here, we review recent research in mice, Drosophila melanogaster and Caenorhabditis elegans, that analyses the molecular and cellular mechanisms underlying decision-making. These studies interrogate decision-making about food, sexual behaviour, aggression or foraging strategies, and add molecular and cell biology understanding onto the consilience of brain and decision.
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