期刊
EMBO MOLECULAR MEDICINE
卷 5, 期 7, 页码 973-983出版社
WILEY
DOI: 10.1002/emmm.201100671
关键词
atherosclerosis; lipid droplet; lipodystrophy; metabolic syndrome; triglyceride storage
资金
- NIH-GMS [R01s GM097194, GM099844]
- Gladstone Institutes
- Mathers Foundation
Lipid droplets (LDs) are dynamic, cytosolic lipid-storage organelles found in nearly all cell types. Too many or too few LDs during excess or deficient fat storage lead to many different human diseases. Recent insights into LD biology and LD protein functions shed new light on mechanisms underlying those metabolic pathologies. These findings will likely provide opportunities for treatment of diseases associated with too much or too little fat.
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