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注意：仅列出部分参考文献，下载原文获取全部文献信息。IQGAP1 and its binding proteins control diverse biological functions
Colin D. White et al.
CELLULAR SIGNALLING (2012)
Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells
Narendra Thapa et al.
DEVELOPMENTAL CELL (2012)
IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold
Miles J. Dixon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
PIPKIγ Regulates β-Catenin Transcriptional Activity Downstream of Growth Factor Receptor Signaling
Mark Schramp et al.
CANCER RESEARCH (2011)
A Screen for Novel Phosphoinositide 3-kinase Effector Proteins
Miles J. Dixon et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
Matthew C. Good et al.
SCIENCE (2011)
Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation
Wei-Ting Chao et al.
JOURNAL OF CELL BIOLOGY (2010)
Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics
Jonathan R. Halstead et al.
JOURNAL OF CELL SCIENCE (2010)
Cell adhesion: integrating cytoskeletal dynamics and cellular tension
J. Thomas Parsons et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
An Emerging Role for IQGAP1 in Regulating Protein Traffic
Mahasin A. Osman
THESCIENTIFICWORLDJOURNAL (2010)
Type I gamma phosphatidylinositol phosphate kinase modulates invasion and proliferation and its expression correlates with poor prognosis in breast cancer
Yue Sun et al.
BREAST CANCER RESEARCH (2010)
Two novel phosphatidylinositol-4-phosphate 5-kinase type Iγ splice variants expressed in human cells display distinctive cellular targeting
Nicholas J. Schill et al.
BIOCHEMICAL JOURNAL (2009)
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration
Tim Laemmermann et al.
BLOOD (2009)
IQGAP1 regulation and roles in cancer
Michael Johnson et al.
CELLULAR SIGNALLING (2009)
IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis
Colin D. White et al.
FEBS LETTERS (2009)
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions
Iman van den Bout et al.
JOURNAL OF CELL SCIENCE (2009)
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
Mika Sakurai-Yageta et al.
JOURNAL OF CELL BIOLOGY (2008)
The PI(3,5)P2 and PI(4,5)P2 Interactomes
Bruno Cadmel et al.
JOURNAL OF PROTEOME RESEARCH (2008)
IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells
Lorraine Jadeski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Fibroblast adaptation and stiffness matching to soft elastic substrates
Jerome Solon et al.
BIOPHYSICAL JOURNAL (2007)
Get to grips: steering local actin dynamics with IQGAPs
Dominique T. Brandt et al.
EMBO REPORTS (2007)
Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases
Yuntao S. Mao et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation
Dominique T. Brandt et al.
JOURNAL OF CELL BIOLOGY (2007)
Type Iγ phosphaticlylinositol phosphate kinase is required for EGF-stimulated directional cell migration
Yue Sun et al.
JOURNAL OF CELL BIOLOGY (2007)
PIP5KIγ is required for cardiovascular and neuronal development
Yanfeng Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
IQGAP1 modulates activation of B-Raf
Jian-Guo Ren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Type Iγ phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with μ1B adaptin
Kun Ling et al.
JOURNAL OF CELL BIOLOGY (2007)
IQGAP1 stimulates actin assembly through the N-WASP-Arp2/3 pathway
Christophe Le Clainche et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A conspicuous connection: Structure defines function for the phosphatidylinositol-phosphate kinase family
Jessica N. Heck et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane
Won Do Heo et al.
SCIENCE (2006)
Phosphoinositides in cell regulation and membrane dynamics
Gilbert Di Paolo et al.
NATURE (2006)
The Nck-interactina kinase ohowhorviates ERM proteins for formation of lamellipodium by growth factors
Martin Baumgartner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Type Iγ661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis
Shawn F. Bairstow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
IQGAP1 in cellular signaling: bridging the GAP
Matthew D. Brown et al.
TRENDS IN CELL BIOLOGY (2006)
Movin' on up: the role of Ptdlns(4,5)P-2 in cell migration
Kun Ling et al.
TRENDS IN CELL BIOLOGY (2006)
Plasma membrane phosphoinositide organization by protein electrostatics
S McLaughlin et al.
NATURE (2005)
IQGAP1: A key regulator of adhesion and migration
J Noritake et al.
JOURNAL OF CELL SCIENCE (2005)
PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility
T Golub et al.
JOURNAL OF CELL BIOLOGY (2005)
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner
ZG Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Regulation of microtubules in cell migration
T Watanabe et al.
TRENDS IN CELL BIOLOGY (2005)
A polybasic motif allows N-WASP to act as a sensor of PIP2 density
V Papayannopoulos et al.
MOLECULAR CELL (2005)
Critical role of PIP5KIγ87 in InsP3-mediated Ca2+ signaling
YJ Wang et al.
JOURNAL OF CELL BIOLOGY (2004)
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
T Watanabe et al.
DEVELOPMENTAL CELL (2004)
Phosphorylation of IQGAP1 modulates its binding to Cdc42, revealing a new type of Rho-GTPase regulator
K Grohmanova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cell migration: Integrating signals from front to back
AJ Ridley et al.
SCIENCE (2003)
IQGAP1 promotes cell motility and invasion
JM Mataraza et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Conserved microtubule-actin interactions in cell movement and morphogenesis
OC Rodriguez et al.
NATURE CELL BIOLOGY (2003)
Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1
ZG Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Phosphoinositide regulation of the actin cytoskeleton
HL Yin et al.
ANNUAL REVIEW OF PHYSIOLOGY (2003)
Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions
K Ling et al.
NATURE (2002)
Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170
M Fukata et al.
CELL (2002)
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI
MA Del Pozo et al.
NATURE CELL BIOLOGY (2002)
IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin
MW Briggs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Involvement of IQGAP1, an effector of Rac1 and Cdc42 GTPases, in cell-cell dissociation during cell scattering
M Fukata et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate
R Rohatgi et al.
JOURNAL OF CELL BIOLOGY (2000)
PIP2 and PIP3: Complex roles at the cell surface
MP Czech
CELL (2000)
Phosphatidylinositol 4,5-bisphoshate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion
D Raucher et al.
CELL (2000)
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