相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Five dysfunctional telomeres predict onset of senescence in human cells
Zeenia Kaul et al.
EMBO REPORTS (2012)
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation
Marzia Fumagalli et al.
NATURE CELL BIOLOGY (2012)
Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells
Michael Y. Sherman et al.
AGING CELL (2011)
A population of BJ fibroblasts escaped from Ras-induced senescence susceptible to transformation
Shinji Kohsaka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Telomeric damage in early stage of chronic lymphocytic leukemia correlates with shelterin dysregulation
Adeline Augereau et al.
BLOOD (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer
Raffaella Di Micco et al.
NATURE CELL BIOLOGY (2011)
TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage
Jing Ye et al.
CELL (2010)
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
Avnish Kapoor et al.
NATURE (2010)
SENESCENCE Senescence in tumours: evidence from mice and humans
Manuel Collado et al.
NATURE REVIEWS CANCER (2010)
Telomerase inhibition induces acute ATM-dependent growth arrest in human astrocytomas
Vincent C. H. Wong et al.
CANCER LETTERS (2009)
Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication
Agnel Sfeir et al.
CELL (2009)
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
Paula Martinez et al.
GENES & DEVELOPMENT (2009)
A two-step model for senescence triggered by a single critically short telomere
Pauline Abdallah et al.
NATURE CELL BIOLOGY (2009)
c-Myc Accelerates S-Phase and Requires WRN to Avoid Replication Stress
Kristin Robinson et al.
PLOS ONE (2009)
A prostatic intraepithelial neoplasia-dependent p27Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression
Pradip K. Majumder et al.
CANCER CELL (2008)
Many roads lead to oncogene-induced senescence
S. Courtois-Cox et al.
ONCOGENE (2008)
An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
SCIENCE (2008)
BRAFE600 in benign and malignant human tumours
C. Michaloglou et al.
ONCOGENE (2008)
DNA damage response mediators MDC1 and 53BP1:: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours
J. Bartkova et al.
ONCOGENE (2007)
Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression
Paolo Giovanni Nuciforo et al.
CARCINOGENESIS (2007)
Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi
Debdutta Bandyopadhyay et al.
AGING CELL (2007)
Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth
Honglin Hao et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
Christopher J. Sarkisian et al.
NATURE CELL BIOLOGY (2007)
Short telomeres limit tumor progression in vivo by inducing senescence
David M. Feldser et al.
CANCER CELL (2007)
Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
Wilfredo Cosme-Blanco et al.
EMBO REPORTS (2007)
P53-dependent integration of telornere and growth factor deprivation signals
Alain Beliveau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Molecular dissection of formation of senescence-associated heterochromatin foci
Rugang Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Accumulation of senescent cells in mitotic tissue of aging primates
Jessie C. Jeyapalan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
Common fragile sites as targets for chromosome rearrangements
Martin F. Arlt et al.
DNA REPAIR (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
Cellular senescence in aging primates
U Herbig et al.
SCIENCE (2006)
Tying the loose ends together in DNA double strand break repair with 53BP1
Melissa M. Adams et al.
CELL DIVISION (2006)
Regulation of growth arrest in senescence: Telomere damage is not the end of the story
U Herbig et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2006)
Lack of poly(ADP-ribose) polymerase-1 gene product enhances cellular sensitivity to arsenite
A Poonepalli et al.
CANCER RESEARCH (2005)
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma
MW Djojosubroto et al.
HEPATOLOGY (2005)
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig et al.
NATURE (2005)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
Major cutbacks at chromosome ends
PM Lansdorp
TRENDS IN BIOCHEMICAL SCIENCES (2005)
The minimal set of genetic alterations required for conversion of primary human fibroblasts to cancer cells in the subrenal capsule assay
BC Sun et al.
NEOPLASIA (2005)
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
NATURE (2005)
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
RG Zhang et al.
DEVELOPMENTAL CELL (2005)
Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects
DA Tuveson et al.
CANCER CELL (2004)
Normal human fibroblasts are resistant to RAS-induced senescence
JA Benanti et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma
AK Meeker et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
In situ analyses of genome instability in breast cancer
K Chin et al.
NATURE GENETICS (2004)
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21CIP1, but not p16INK4a
U Herbig et al.
MOLECULAR CELL (2004)
Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis
AK Meeker et al.
CLINICAL CANCER RESEARCH (2004)
A DNA damage checkpoint response in telomere-initiated senescence
FD di Fagagna et al.
NATURE (2003)
DNA damage foci at dysfunctional telomeres
H Takai et al.
CURRENT BIOLOGY (2003)
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
KK Wong et al.
NATURE (2003)
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
KL Rudolph et al.
NATURE GENETICS (2001)
p53 Binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
LB Schultz et al.
JOURNAL OF CELL BIOLOGY (2000)
分享论文
