相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。ATM and the Molecular Pathogenesis of Ataxia Telangiectasia
Peter J. McKinnon
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)
Mechanisms of Inhibition within the Telencephalon: Where the Wild Things Are
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Mre11 Nuclease Activity and Ctp1 Regulate Chk1 Activation by Rad3ATR and Tel1ATM Checkpoint Kinases at Double-Strand Breaks
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MOLECULAR AND CELLULAR BIOLOGY (2011)
Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR
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A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
Luis I. Toledo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Selective Deletion of a Cell Cycle Checkpoint Kinase (ATR) Reduces Neurogenesis and Alters Responses in Rodent Models of Behavioral Affect
Jennifer L. Onksen et al.
NEUROPSYCHOPHARMACOLOGY (2011)
A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling
Cecilia Cotta-Ramusino et al.
SCIENCE (2011)
Combining ATR Suppression with Oncogenic Ras Synergistically Increases Genomic Instability, Causing Synthetic Lethality or Tumorigenesis in a Dosage-Dependent Manner
Oren Gilad et al.
CANCER RESEARCH (2010)
Treslin Collaborates with TopBP1 in Triggering the Initiation of DNA Replication
Akiko Kumagai et al.
CELL (2010)
The ATR barrier to replication-born DNA damage
Andres J. Lopez-Contreras et al.
DNA REPAIR (2010)
A vertebrate gene, ticrr, is an essential checkpoint and replication regulator
Christopher L. Sansam et al.
GENES & DEVELOPMENT (2010)
DNA Damage Signaling Recruits the Rtt107-SIx4 Scaffolds via Dpb11 to Mediate Replication Stress Response
Patrice Y. Ohouo et al.
MOLECULAR CELL (2010)
Damage-induced phosphorylation of Sld3 is important to block late origin firing
Jaime Lopez-Mosqueda et al.
NATURE (2010)
Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation
Philip Zegerman et al.
NATURE (2010)
Maintaining genome stability at the replication fork
Dana Branzei et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
THE FORKHEAD TRANSCRIPTION FACTORS, Foxp1 AND Foxp2, IDENTIFY DIFFERENT SUBPOPULATIONS OF PROJECTION NEURONS IN THE MOUSE CEREBRAL CORTEX
T. Hisaoka et al.
NEUROSCIENCE (2010)
Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells
Nozomi Tomimatsu et al.
EMBO REPORTS (2009)
ATR signaling at a glance
Bunsyo Shiotani et al.
JOURNAL OF CELL SCIENCE (2009)
Crystal Structure of the Human Rad9-Hus1-Rad1 Clamp
Sun Young Sohn et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM
Hae Yong Yoo et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks
Bunsyo Shiotani et al.
MOLECULAR CELL (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53
Yaroslava Ruzankina et al.
NATURE GENETICS (2009)
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Matilde Murga et al.
NATURE GENETICS (2009)
Dual and opposing roles of primary cilia in medulloblastoma development
Young-Goo Han et al.
NATURE MEDICINE (2009)
Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex
Shen-Ju Chou et al.
NATURE NEUROSCIENCE (2009)
The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1
Youngsoo Lee et al.
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DNA repair deficiency and neurological disease
Peter J. McKinnon
NATURE REVIEWS NEUROSCIENCE (2009)
Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool
N. Spassky et al.
DEVELOPMENTAL BIOLOGY (2008)
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
Daniel A. Mordes et al.
GENES & DEVELOPMENT (2008)
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
Xin Xu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
ATR: an essential regulator of genome integrity
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In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus
Hoonkyo Suh et al.
CELL STEM CELL (2007)
The Rad9-Hus1-Rad1 checkpoint interaction of TopBP1 with ATR
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool
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JOURNAL OF NEUROSCIENCE (2007)
Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes
Nuria Flames et al.
JOURNAL OF NEUROSCIENCE (2007)
Patched1 regulates Hedgehog signaling at the primary cilium
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SCIENCE (2007)
Deletion of the developmentallv essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss
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CELL STEM CELL (2007)
Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM
Hae Yong Yoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
Sinny Delacroix et al.
GENES & DEVELOPMENT (2007)
Neuronal subtype specification in the cerebral cortex
Bradley J. Molyneaux et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Cell-cycle control and cortical development
Colette Dehay et al.
NATURE REVIEWS NEUROSCIENCE (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Responding to DNA double strand breaks in the nervous system
Y. Lee et al.
NEUROSCIENCE (2007)
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
Anna V. Molofsky et al.
NATURE (2006)
The ATM-mediated DNA-damage response: taking shape
Yosef Shiloh
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development
Kenji E. Orii et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
TopBP1 activates the ATR-ATRIP complex
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CELL (2006)
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
M Cuadrado et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
ATR activation in response to ionizing radiation: still ATM territory
Myriam Cuadrado et al.
CELL DIVISION (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
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Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA
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Selective lengthening of the cell cycle in the neurogenic subpopulation of neural progenitor cells during mouse brain development
F Calegari et al.
JOURNAL OF NEUROSCIENCE (2005)
Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage
J Rouse
EMBO JOURNAL (2004)
Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures
F Sar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together
TH Stracker et al.
DNA REPAIR (2004)
Ataxia-telangiectasia, an evolving phenotype
HH Chun et al.
DNA REPAIR (2004)
ATR and ATM regulate the timing of DNA replication origin firing
D Shechter et al.
NATURE CELL BIOLOGY (2004)
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
JMD Corrales et al.
DEVELOPMENT (2004)
Hedgehog signalling in the mouse requires intraflagellar transport proteins
DW Huangfu et al.
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Human claspin is required for replication checkpoint control
C Christiano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
M O'Driscoll et al.
NATURE GENETICS (2003)
Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17
J Lee et al.
MOLECULAR CELL (2003)
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
A Kumagai et al.
NATURE CELL BIOLOGY (2003)
Live or let die: The cell's response to p53
KH Vousden et al.
NATURE REVIEWS CANCER (2002)
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
KP Hopfner et al.
NATURE (2002)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
A long, remarkable journey:: Tangential migration in the telencephalon
O Marín et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Telencephalic cells take a tangent: non-radial migration in the mammalian forebrain
JG Corbin et al.
NATURE NEUROSCIENCE (2001)
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
H Zhao et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Seckel's syndrome and malformations of cortical development: Report of three new cases and review of the literature
G Capovilla et al.
JOURNAL OF CHILD NEUROLOGY (2001)
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
A de Klein et al.
CURRENT BIOLOGY (2000)
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development
YJ Gao et al.
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