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注意：仅列出部分参考文献，下载原文获取全部文献信息。A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development
Ellen J. Ezratty et al.
CELL (2011)
Asymmetric cell divisions promote Notch-dependent epidermal differentiation
Scott E. Williams et al.
NATURE (2011)
Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates
Oe Yalcin-Ozuysal et al.
CELL DEATH AND DIFFERENTIATION (2010)
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1
Carrie A. Ambler et al.
DEVELOPMENT (2010)
Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice
Helen A. Thomason et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias
Francesca Moretti et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Opposing roles for calcineurin and ATF3 in squamous skin cancer
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Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin
Alexis Dumortier et al.
PLOS ONE (2010)
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
Marco Mazzone et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
Raphael Kopan et al.
CELL (2009)
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
Yumi Yashiro-Ohtani et al.
GENES & DEVELOPMENT (2009)
Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
Suresh Cuddapah et al.
GENOME RESEARCH (2009)
Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence
Rebecca J. Richardson et al.
HUMAN MOLECULAR GENETICS (2009)
A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans
Anna Mandinova et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Skin-Derived TSLP Triggers Progression from Epidermal-Barrier Defects to Asthma
Shadmehr Demehri et al.
PLOS BIOLOGY (2009)
Crosstalk of Notch with p53 and p63 in cancer growth control
G. Paolo Dotto
NATURE REVIEWS CANCER (2009)
The IRF family transcription factors in immunity and oncogenesis
Tomohiko Tamura et al.
ANNUAL REVIEW OF IMMUNOLOGY (2008)
IRF6 in development and disease - A mediator of quiescence and differentiation
Caleb M. Bailey et al.
CELL CYCLE (2008)
Epidermal Notch signalling: differentiation, cancer and adhesion
Fiona M. Watt et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis
Xuan Wang et al.
JOURNAL OF CELL BIOLOGY (2008)
Role of the Notch ligand Delta1 in embryonic and adult mouse epidermis
Soline Estrach et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)
Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner
Caleb M. Bailey et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
Vihren Kolev et al.
NATURE CELL BIOLOGY (2008)
Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip
Fedik Rahimov et al.
NATURE GENETICS (2008)
Rational targeting of Notch signaling in cancer
P. Rizzo et al.
ONCOGENE (2008)
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
Nathaniel D. Heintzman et al.
NATURE GENETICS (2007)
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases
Karine Lefort et al.
GENES & DEVELOPMENT (2007)
p63 regulates proliferation and differentiation of developmentally mature keratinocytes
Amy B. Truong et al.
GENES & DEVELOPMENT (2006)
Canonical Notch signaling functions as a commitment switch in the epidermal lineage
Cedric Blanpain et al.
GENES & DEVELOPMENT (2006)
Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch
Rebecca J. Richardson et al.
NATURE GENETICS (2006)
Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)
Christopher R. Ingraham et al.
NATURE GENETICS (2006)
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
BC Nguyen et al.
GENES & DEVELOPMENT (2006)
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA
JJ Wilson et al.
CELL (2006)
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes
Y Nam et al.
CELL (2006)
Notch signalling: a simple pathway becomes complex
Sarah J. Bray
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Mammary serine protease inhibitor (maspin) binds directly to interferon regulatory factor 6 - Identification of a novel serpin partnership
CM Bailey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
P21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
V Devgan et al.
GENES & DEVELOPMENT (2005)
The role of p63 in development and differentiation of the epidermis
MI Kostera et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2004)
p63: molecular complexity in development and cancer
MD Westfall et al.
CARCINOGENESIS (2004)
γ-secretase functions through notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis
YH Pan et al.
DEVELOPMENTAL CELL (2004)
Notch1 functions as a tumor suppressor in mouse skin
M Nicolas et al.
NATURE GENETICS (2003)
HES and HERP families: Multiple effectors of the Notch signaling pathway
T Iso et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Notch/RBP-J signaling regulates epidermis/hair fate determination of hair follicular stem cells
N Yamamoto et al.
CURRENT BIOLOGY (2003)
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
M Dajee et al.
NATURE (2003)
CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis
M Lazarov et al.
NATURE MEDICINE (2002)
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
S Kondo et al.
NATURE GENETICS (2002)
Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ
BJ Nickoloff et al.
CELL DEATH AND DIFFERENTIATION (2002)
Structure and function of IRF-7
LW Zhang et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2002)
Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
SR Frank et al.
GENES & DEVELOPMENT (2001)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A Rangarajan et al.
EMBO JOURNAL (2001)
Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size
JE Dazard et al.
ONCOGENE (2000)
Notch signalling via RBP-J promotes myeloid differentiation
T Schroeder et al.
EMBO JOURNAL (2000)
Stimulation of human epidermal differentiation by Delta-Notch signalling at the boundaries of stem-cell clusters
S Lowell et al.
CURRENT BIOLOGY (2000)
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