期刊
ELECTROPHORESIS
卷 34, 期 14, 页码 2011-2016出版社
WILEY
DOI: 10.1002/elps.201300056
关键词
Electrochemistry; Fluidic microsystem; Nanostructurated CaCO3-poly(ethylene-imine) microparticles; Phenolic compounds
资金
- Scientific Grant Agency VEGA of the Slovak Republic [1/0182/11]
- MICINN (Spain) [PIB2010JP-00278]
- Generalitat of Catalunya
- ICREA Funding Source: Custom
A new and simple strategy based on nanostructured CaCO3-poly(ethyleneimine) (PEI) microparticles (MPs) for phenol sensing using PDMS/glass fluidic microchip is developed. This fluidic microsystem including integrated screen-printed electrodes modified with CaCO3-PEI MPs and tyrosinase (Tyr) through cross-linking with glutaraldehyde, represents a low-cost platform for phenol detection. The designed fluidic microsystem improves the sensitivity of the biosensor allowing the detection of very low concentrations of phenol (up to 10 nM). This device shows high repeatability and low detection limit, is easy to be fabricated, inexpensive, disposable, and amenable to mass production.
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