相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Hyperphosphorylated Tau is a Cause of Neuronal Dysfunction in Tauopathy
Akihiko Takashima
JOURNAL OF ALZHEIMERS DISEASE (2017)
α-Synuclein misfolding and Parkinson's disease
Leonid Breydo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Alzheimer culprits: Cellular crossroads and interplay
Sylvie Claeysen et al.
CELLULAR SIGNALLING (2012)
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
Lucia Chavez-Gutierrez et al.
EMBO JOURNAL (2012)
Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain
Aarti N. Patel et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2012)
Prion-like spread of protein aggregates in neurodegeneration
Magdalini Polymenidou et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of β-Amyloid
Sangeeta Nath et al.
JOURNAL OF NEUROSCIENCE (2012)
Transgenic Expression of Intraneuronal Aβ42 But Not Aβ40 Leads to Cellular Aβ Lesions, Degeneration, and Functional Impairment without Typical Alzheimer's Disease Pathology
Dorothee Abramowski et al.
JOURNAL OF NEUROSCIENCE (2012)
Endoplasmic Reticulum Enrollment in Alzheimer's Disease
Ricardo J. S. Viana et al.
MOLECULAR NEUROBIOLOGY (2012)
Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
Justin M. Nussbaum et al.
NATURE (2012)
The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE
Rita J. Guerreiro et al.
NEUROBIOLOGY OF AGING (2012)
Integrating the Alzheimer's Disease Proteome and Transcriptome: A Comprehensive Network Model of a Complex Disease
Peter Hallock et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)
Trans-Synaptic Spread of Tau Pathology In Vivo
Li Liu et al.
PLOS ONE (2012)
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons
Martin Lundblad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease
Yunqi Xu et al.
PROGRESS IN NEUROBIOLOGY (2012)
The cholinergic system in aging and neuronal degeneration
Reinhard Schliebs et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches
Ronald J. Hause et al.
EXPERT REVIEW OF PROTEOMICS (2011)
Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation
Jack Reifert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Interactions of Pathological Hallmark Proteins TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN
Judit Olah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Tau Protein Is Required for Amyloid β-Induced Impairment of Hippocampal Long-Term Potentiation
Olivia A. Shipton et al.
JOURNAL OF NEUROSCIENCE (2011)
A Quantitative Proteomic Approach to Prion Disease Biomarker Research: Delving into the Glycoproteome
Xin Wei et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Protein Array Based Interactome Analysis of Amyloid-β Indicates an Inhibition of Protein Translation
Dezso P. Virok et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Back to the basics: Maximizing the information obtained by quantitative two dimensional gel electrophoresis analyses by an appropriate experimental design and statistical analyses
Luis Valledor et al.
JOURNAL OF PROTEOMICS (2011)
In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging
Gabriele S. Kaminski Schierle et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Neuronal transport: myosins pull the ER
Michael Stiess et al.
NATURE CELL BIOLOGY (2011)
Amyloid-β and tau - a toxic pas de deux in Alzheimer's disease
Lars M. Ittner et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Post-translational modifications of tau protein: Implications for Alzheimer's disease
Ludovic Martin et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
Systems biology of Alzheimer's disease: How diverse molecular changes result in memory impairment in AD
Gabor Juhasz et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
Diagnosis of Alzheimer's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera
Eric Nagele et al.
PLOS ONE (2011)
The Molecular Assembly of Amyloid Aβ Controls Its Neurotoxicity and Binding to Cellular Proteins
Claudia Manzoni et al.
PLOS ONE (2011)
Subcellular proteomics revealed the epithelial-mesenchymal transition phenotype in lung cancer
Li-Ping Li et al.
PROTEOMICS (2011)
The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology
M.L. Giuffrida et al.
REVIEWS IN THE NEUROSCIENCES (2011)
Proteostasis and Movement Disorders: Parkinson's Disease and Amyotrophic Lateral Sclerosis
Daryl A. Bosco et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease
Gunnar K. Gouras et al.
ACTA NEUROPATHOLOGICA (2010)
Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
Lars M. Ittner et al.
CELL (2010)
Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex
Patricia V. Burgos et al.
DEVELOPMENTAL CELL (2010)
Alzheimer Disease
Rudy J. Castellani et al.
DM DISEASE-A-MONTH (2010)
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
Irina Kuperstein et al.
EMBO JOURNAL (2010)
Quantitative phosphoproteomic analysis of neuronal intermediate filament proteins (NF-M/H) in Alzheimer's disease by iTRAQ
Parvathi Rudrabhatla et al.
FASEB JOURNAL (2010)
Immunohistochemical Visualization of Amyloid-beta Protein Precursor and Amyloid-beta in Extra- and Intracellular Compartments in the Human Brain
Leena Aho et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Synthetic Triterpenoids Target the Arp2/3 Complex and Inhibit Branched Actin Polymerization
Ciric To et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A guide to super-resolution fluorescence microscopy
Lothar Schermelleh et al.
JOURNAL OF CELL BIOLOGY (2010)
An update on clinical proteomics in Alzheimer's research
Minna A. Korolainen et al.
JOURNAL OF NEUROCHEMISTRY (2010)
A Mouse Model of Amyloid β Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
Takami Tomiyama et al.
JOURNAL OF NEUROSCIENCE (2010)
Two-dimensional gel electrophoresis in proteomics: Past, present and future
Thierry Rabilloud et al.
JOURNAL OF PROTEOMICS (2010)
ADDLs and the signaling web that leads to Alzheimer's disease
Grant A. Krafft et al.
NEUROPHARMACOLOGY (2010)
Development and Validation of a Method for Profiling Post-Translational Modification Activities Using Protein Microarrays
Sonia V. del Rincon et al.
PLOS ONE (2010)
Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis
Yvonne S. Eisele et al.
SCIENCE (2010)
Classification and basic pathology of Alzheimer disease
Charles Duyckaerts et al.
ACTA NEUROPATHOLOGICA (2009)
Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
Oliver Wirths et al.
ACTA NEUROPATHOLOGICA (2009)
Mechanisms of tau-induced neurodegeneration
Khalid Iqbal et al.
ACTA NEUROPATHOLOGICA (2009)
Clathrin-mediated endocytosis and Alzheimer's disease: An update
Fangbai Wu et al.
AGEING RESEARCH REVIEWS (2009)
The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus
Jeroen J. M. Hoozemans et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Neuropathology of Lewy body disorders
Enikoe Koevari et al.
BRAIN RESEARCH BULLETIN (2009)
The amyloid hypothesis for Alzheimer's disease: a critical reappraisal
John Hardy
JOURNAL OF NEUROCHEMISTRY (2009)
Low molecular weight Aβ induces collapse of endoplasmic reticulum
Cora Sau-Wan Lai et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
NEUROSCIENCE Alzheimer's disease
Lennart Mucke
NATURE (2009)
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
Virginie Rhein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cytoskeletal Pathologies of Alzheimer Disease
James R. Bamburg et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
Clinical proteomics in neurodegenerative disorders
H. Zetterberg et al.
ACTA NEUROLOGICA SCANDINAVICA (2008)
Mass spectrometry for proteomics
Xuemei Han et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1
Bryan F. Shaw et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Flotillin-dependent clustering of the amyloid precursor protein regulates its endocytosis and amyloidogenic processing in neurons
Anja Schneider et al.
JOURNAL OF NEUROSCIENCE (2008)
ER stress is involved in Aβ-induced GSK-3β activation and tau phosphorylation
Rosa Resende et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Characterization of the interaction between A beta 1-42 and glyceraldehyde phosphodehydrogenase
Yann Verdier et al.
JOURNAL OF PEPTIDE SCIENCE (2008)
The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
Camilla A. Hansson Petersen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma:: Evidence for novel Aβ species
Juan Manuel Maler et al.
PROTEOMICS (2007)
The role of intracellular amyloid β in Alzheimer's disease
Meng Li et al.
PROGRESS IN NEUROBIOLOGY (2007)
A la carte proteomics with an emphasis on gel-free techniques
Kris Gevaert et al.
PROTEOMICS (2007)
Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Endoplasmic reticulum chaperones inhibit the production of amyloid-β peptides
Tatsuya Hoshino et al.
BIOCHEMICAL JOURNAL (2007)
Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Aβ interaction
Yilin Yan et al.
BIOCHEMISTRY (2007)
Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition
Frank Gillardon et al.
PROTEOMICS (2007)
Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: A role for intraneuronal amyloid
L. Gimenez-Llort et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2007)
Mitochondrial Aβ:: A potential cause of metabolic dysfunction in Alzheimer's disease
Xi Chen et al.
IUBMB LIFE (2006)
Intracellular amyloid β-protein and its associated molecules in the pathogenesis of Alzheimer's disease
Yasumasa Ohyagi et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2006)
Physiological roles for amyloid β peptides
Hugh A. Pearson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis
KI Willig et al.
NATURE (2006)
Autophagy in neurodegenerative disease: friend, foe or turncoat?
Ralph A. Nixon
TRENDS IN NEUROSCIENCES (2006)
Endoplasmic reticulum stress: cell life and death decisions
CY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Limitations of current proteomics technologies
S Garbis et al.
JOURNAL OF CHROMATOGRAPHY A (2005)
Down syndrome, Alzheimer's disease and seizures
M Menéndez
BRAIN & DEVELOPMENT (2005)
Intraneuronal Aβ causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
LM Billings et al.
NEURON (2005)
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-β1-42
PJ Crouch et al.
JOURNAL OF NEUROSCIENCE (2005)
Tau pathology in Alzheimer disease and other tauopathies
K Iqbal et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)
FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein
CU Pietrzik et al.
JOURNAL OF NEUROSCIENCE (2004)
ABAD directly links Aβ to mitochondrial toxicity in Alzheimer's disease
JW Lustbader et al.
SCIENCE (2004)
Massive CA1/2 neuronal loss with intraneuronal and N-interminal truncated Aβ42 accumulation in a novel Alzheimer transgenic model
C Casas et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Cytosolic and nuclear aggregation of the amyloid β-peptide following its expression in the endoplasmic reticulum
A Bückig et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2002)
Intraneuronal Alzheimer Aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
RH Takahashi et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis
GL Xu et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2002)
Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease
RG Nagele et al.
NEUROSCIENCE (2002)
Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease
C Glabe
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)
Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease
K Ditaranto et al.
NEUROBIOLOGY OF DISEASE (2001)
Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease
MR D'Andrea et al.
HISTOPATHOLOGY (2001)
Endocytic pathway abnormalities precede amyloid β deposition in sporadic Alzheimer's disease and Down syndrome -: Differential effects of APOE genotype and presenilin mutations
AM Cataldo et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Intraneuronal A beta 42 accumulation in human brain
GK Gouras et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
分享论文
