期刊
ELECTROPHORESIS
卷 31, 期 18, 页码 3014-3027出版社
WILEY
DOI: 10.1002/elps.201000137
关键词
Axon guidance; Chemotaxis; Gradient; Microfluidics; Stem cell differentiation
资金
- Ministry of Education, Science and Technology [R11-2008-044-01002-0]
- Korea Industrial Technology Foundation (KOTEF)
Concentration gradients play an important role in controlling biological and pathological processes, such as metastasis, embryogenesis, axon guidance, and wound healing. Microfluidic devices fabricated by photo- and soft lithography techniques can manipulate the fluidic flow and diffusion profile to create biomolecular gradients in a temporal and spatial manner. Furthermore, microfluidic devices enable the control of cell-extracellular microenvironment interactions, including cell cell, cell matrix, and cell soluble factor interaction. In this paper, we review the development of microfluidic-based gradient devices and highlight their biological applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据