CE with MS detection: A rapidly developing hyphenated technique

Thirty years of Electrophoresis - 22 years of CE-MS; what has happened to this hyphenated technique within the last decades? Was it able to develop from a scientifically interesting and promising but exotic technique, available exclusively to a restricted group of users with pronounced technical skills, to an almost routine technique (at least in some fields of application) performed on commercially available equipment? What might be the future of CE-MS with respect to technical developments or new fields of application? The present review paper will try to provide answers to some of these questions. Current progress as well as possible future directions in CE-MS will be displayed using the example of selected publications from several areas.