期刊
JOURNAL OF PHYSIOLOGICAL SCIENCES
卷 66, 期 1, 页码 77-83出版社
SPRINGER JAPAN KK
DOI: 10.1007/s12576-015-0398-z
关键词
Supraclavicular skin temperature; BAT activity; Human adults; iButtons; PET/CT-imaging
类别
资金
- Netherlands Organization for Scientific Research [TOP 91209037]
- EU FP7 project DIABAT [HEALTH-F2-2011-278373]
The 'gold standard' for measuring brown adipose tissue (BAT) in humans is [F-18]FDG-PET/CT-imaging. With this technique subjects are exposed to ionizing radiation and are therefore limited in the number of scans that can be performed. We investigated the relation between supraclavicular skin temperatures and BAT activity values using a strictly temperature-controlled air-cooling protocol. Data of 36 male subjects was analyzed. BAT activity was evaluated by [F-18]FDG-PET/CT-imaging and skin temperature was measured by means of wireless temperature sensors. Supraclavicular skin temperature dropped less compared to skin temperatures at other sites (all P values < 0.01). A significant positive correlation was found between the change in supraclavicular skin temperature with BAT activity (R (2) 0.23), and the change in supraclavicular skin temperature and non-shivering thermogenesis (R (2) 0.18, both P values < 0.01). The correlations indicate that supraclavicular skin temperature (changes) can potentially be used as a qualitative measure of BAT activity and BAT thermogenesis.
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