期刊
ELECTROCHEMISTRY COMMUNICATIONS
卷 11, 期 10, 页码 1869-1872出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2009.08.006
关键词
Human immunoglobulin E (IgE); Methylene blue (MB); Gold nanoparticles (GNPs)
资金
- National Basic Research Program [2007CB310500]
- National Natural Science Foundation of China [90817101, 20675028, 20775023, 20865006]
- Hunan Provincial Natural Science Foundation [07JJ6101, 07IJ3017]
- Hunan Provincial Education Department [08A065]
A label-free electrochemical immunosensor for the detection of protein analytes without redox-active centers is for the first time developed based on the combination of gold nanoparticles and the mediated charge transport through the multilayer films that is related to an electrocatalytic process. Given the low detection limit, high sensitivity and selectivity, the success achieved here seems plausibly to serve as a significant step toward the development of versatile label-free immunoassay. (C) 2009 Elsevier B.V. All rights reserved.
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