Nanocrystalline Metallosilicate Modified Electrodes for the Simultaneous, Sensitive, and Selective Determination of Riboflavin, Rutin, and Pyridoxine

Nanocrystalline metallosilicate modified glassy carbon electrodes were fabricated for the simultaneous determination of vitamins. Among these, nanocrystalline zirconosilicate exhibited the highest activity with a linear range from 30nM-500 mu M for riboflavin and 120nM-600 mu M for rutin and pyridoxine. Sensitivity values of 2.8, 1.49, and 1.13 mu A/mu M cm(2) and lower detection limits of 5nM, 30nM, and 30nM for riboflavin, rutin, and pyridoxine, respectively, were found. The proposed sensor is stable and reproducible (RSD<3.5%). The analytical performance of this sensor was demonstrated in the pharmaceutical preparations (multivitamin tablets) with satisfactory recovery (97-103%).