期刊
ELECTROANALYSIS
卷 24, 期 5, 页码 1220-1225出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201200062
关键词
Quantum dots; Electrochemiluminescence
资金
- National Natural Science Foundation of China [21175078, 21075073]
- Natural Science Foundation of Shandong Province [ZR2010BZ003]
A novel dendritic CdS-ZnS-Quantum Dots (QDs) nanocomposite with intense electrochemiluminescence (ECL) and excellent magnetism was prepared, which was applied to the cancer cells assay based on ECL quenching of QDs by gold nanoparticles (NPs). DNA conjugation, gold NPs linking and sensing target cells can be directly performed on the magnetic nanocomposites, which is more rapid, convenient, and has better reproducibility than the conventional methods. So far, this is the first report on magnetic electrochemiluminescent QDs nanocomposites for cell detection based on ECL quenching, which opens a new approach for developing multifunctional QDs nanocomposite for ECL assays of cancer cells.
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