期刊
ELECTROANALYSIS
卷 24, 期 11, 页码 2125-2133出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201200292
关键词
Sulfonamides; Amperometry; Chromatography; Meat-based samples
资金
- Ministero dell'Universita e della Ricerca Scientifica e Tecnologica (Cofin)
Sulfonamides were oxidized at a polycrystalline gold electrode in neutral buffered phosphate medium at pH 7 and the electrochemical behavior was investigated using cyclic voltammetry technique. A liquid chromatography methodology based on the C-18 reverse phase for the simultaneous separation of nine sulfamides, was studied and optimized. The amperometric detector using a polycrystalline gold substrate as working electrode and operating under pulsed amperometric detection mode (PAD) was tested for the determination of the selected molecules. Under optimal chromatographic and amperometric conditions, the limit of detection of the investigated sulfamides are comprised between 1 mu M and 0.05 mu M and the dynamic linear range spanned generally over three orders of magnitude. A liquid extraction procedure based on the use of acetonitrile solvent was tested and proposed for the quantitative extraction of sulfonamides from homogenized meat samples. The analytical method was successful tested for the determination of sulfonamides in homogenized meat-based baby foods with reproducibility and recovery levels ranged between 5.0?% and 7.6?%. and 86?%106?%, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据