期刊
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
卷 76, 期 -, 页码 126-134出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2011.10.007
关键词
Pelteobagrus fulvidraco; Copper toxicity; Calcium; Hepatic metabolism; Histology; Copper accumulation
资金
- National Natural Science Foundation of China [31072226]
- Fundamental Research Funds for the Central Universities of China [52204-10078, 52902-0900202141]
The present study was conducted to determine interactive effects of waterborne co-exposure of copper (Cu) and calcium (Ca) on Cu accumulation, enzymatic activities and histology in yellow catfish Pelteobagrus fulvidraco and test the prediction that Ca could protect against Cu-induced toxicity in the fish species. Yellow catfish were exposed to 0, 1.0, 2.0 mg Cu/l, in combination with 0 and 50 mg Ca/l. Waterborne Cu and Ca co-exposure influenced the majority of tested enzymatic activities (succinate dehydrogenase, malic dehydrogenase, lactate dehydrogenase, lipoprotein lipase and hepatic lipase), and changed Cu contents in several organs (gill, liver, kidney, gastrointestine and muscle). For histological observations, at the same Ca level, waterborne Cu exposure induced injuries in gills and liver. However, Ca addition seemed to mitigate the severity of Cu-induced injuries. Thus, our study demonstrated that Ca had the capacity to reduce Cu toxicity in P. fulvidraco. (C) 2011 Elsevier Inc. All rights reserved.
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