期刊
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
卷 72, 期 6, 页码 1798-1804出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2009.05.002
关键词
1-alkyl-3-methylimidazolium bromide; Ionic liquid; Daphnia magna; Acute toxicity; Antioxidant enzyme; Lipid peroxidation
资金
- National Science Foundation of China [20573019, 20573034]
- Henan innovation Project for University Prominent Research Talents [2006KCX021]
- Research Project of the Ministry of Education of China [[2006]331]
- Research Project of Henan Normal University [521838, 052063]
- Key Subjects of Fishery in Henan Province, China
This study examined the antioxidant responses of Daphnia magna following exposure to different concentrations of the ionic liquid (IL) 1-octyl-3-methylimidazolium bromide and the 50% LC50 concentrations of methylimidazolium bromide ILs with different alkyl-chain lengths. Activities of antioxidant defense enzymes (superoxide dismutase, catalase, glutathione peroxidase, and glutathione S-transferase) and levels of the antioxidant glutathione and the lipid peroxidation by-product malondialdehyde were measured using traditional methods or commercial kits. The concentration and the alkyl-chain length of ILs were found to strongly influence the antioxidant system of D. magna following IL exposure, and exposure to higher IL concentrations and to ILs with longer alkyl chains generally increased the enzyme activities and biomarker levels examined. Therefore, the present study suggests that oxidative stress is involved in the mechanism of IL-induced toxicity in D. magna. (C) 2009 Elsevier Inc. All rights reserved.
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