期刊
ECOHEALTH
卷 15, 期 4, 页码 864-870出版社
SPRINGER
DOI: 10.1007/s10393-018-1364-z
关键词
Yellow fever virus; Non-human primates; Emerging infectious diseases; Zoonotic virus; Arboviruses; Outbreak
资金
- Brazilian agency CAPES
- Brazilian agency CNPq
- MCTIC/FNDCT-CNPq/ MEC-CAPES/ MS-Decit [14/2016]
At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population.
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