期刊
EARLY HUMAN DEVELOPMENT
卷 84, 期 12, 页码 809-814出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2008.09.009
关键词
Neonatal; Newborn; Research; Priority-setting; Neonatal infections; Preterm birth; Birth asphyxia; Inequity; Epidemiology; Millennium Development Goals
资金
- Bill & Melinda Gates Foundation
- Seattle Children's Hospital
Four million neonates die each year. These deaths are mostly in low-income countries, but neonatal mortality and morbidity are also a priority burden in high-income countries. Epidemiological evidence suggests newborn research would prioritise the poorest families: birth and the first days of life; major causes particularly infections, preterm birth and asphyxia: and include preventive strategies as well as improved care. However research investment is not commensurate to burden, and there is a mismatch with current research priorities. South Asia and sub Saharan Africa. with 75% of the burden, expend around US$20 million per year on newborn research, a fraction of what is spent on a smaller proportion of health problem in rich countries. We propose a research pipeline of description, discovery, development of solutions and delivery of research with scale-up to reach the poorest families. Listing research options and applying quantitative scoring enables systematic, transparent research prioritisation. As well as a research pipeline, a people pipeline is required to generate research capacity in low-income countries. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
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