期刊
DYES AND PIGMENTS
卷 107, 期 -, 页码 127-132出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2014.03.012
关键词
Fluorescein; Hypochlorite anion; Biological imaging; Water solubility; Flourescent probe; Spirolactam
资金
- Jiangsu Key Laboratory of Industrial Water Conservation & Emission Reduction
- National Basic Research Program of China (973 Program) [2014CB846004]
A highly sensitive and selective fluorescein-based probe 1 for hypochlorite anion was synthesized. The probe 1 has favorable characteristics for biological imaging, including high water solubility, high fluorescence yield, pH-independent fluorescence, and biocompatibility. Results show that it has a detection limit of 40 nM to hypochlorite anion. In addition, confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new probe 1 could be used as an effective fluorescent probe for detecting HOC in living cells. (C) 2014 Elsevier Ltd. All rights reserved.
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