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5TH DRUG DESIGN & LEAD DISCOVERY CONFERENCE 2009: LEAD FINDING STRATEGIES AND OPTIMIZATION CASE STUDIES

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DRUGS OF THE FUTURE
卷 35, 期 2, 页码 143-153

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PROUS SCIENCE, SAU-THOMSON REUTERS
DOI: 10.1358/dof.2010.035.02.1468927

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This review reports the most important contributions of the 5(th) Drug Design & Lead Discovery conference, held in October 2009 in San Diego. The conference was focused on lead-finding strategies and compound optimization. Lectures covered state-of-the-art design strategies, application fragment-based approaches, the impact of ADME properties on lead finding and optimization, and a number of optimization case studies, In addition to the new technologies reported, both fragment-based and optimization case studies provided excellent examples for the lead discovery knowledge space that was discussed in detail during the conference.

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