相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX
Ashima Saxena et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs
Manojkumar Valiyaveettil et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon
E. G. Duysen et al.
GENE THERAPY (2011)
Computational characterization of how the VX nerve agent binds human serum paraoxonase 1
Steven Z. Fairchild et al.
JOURNAL OF MOLECULAR MODELING (2011)
Gene-Delivered Butyrylcholinesterase Is Prophylactic against the Toxicity of Chemical Warfare Nerve Agents and Organophosphorus Compounds
Kalpana Parikh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Directed evolution of hydrolases for prevention of G-type nerve agent intoxication
Rinkoo D. Gupta et al.
NATURE CHEMICAL BIOLOGY (2011)
Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme
Andrew C. Hemmert et al.
PLOS ONE (2011)
Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents
Marie Trovaslet-Leroy et al.
TOXICOLOGY LETTERS (2011)
Evolution of and perspectives on therapeutic approaches to nerve agent poisoning
Patrick Masson
TOXICOLOGY LETTERS (2011)
Kinetics and Efficacy of an Organophosphorus Hydrolase in a Rodent Model of Methyl-parathion Poisoning
Chip Gresham et al.
ACADEMIC EMERGENCY MEDICINE (2010)
Butyrylcholinesterase for protection from organophosphorus poisons: Catalytic complexities and hysteretic behavior
Patrick Masson et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1
Manojkumar Valiyaveettil et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Structural Insights into the Dual Activities of the Nerve Agent Degrading Organophosphate Anhydrolase/Prolidase
Nand K. Vyas et al.
BIOCHEMISTRY (2010)
Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae
Tamara C. Otto et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2010)
Hyperthermophilic phosphotriesterases/lactonases for the environment and human health
Luigi Mandrich et al.
ENVIRONMENTAL TECHNOLOGY (2010)
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol
Boris N. Novikov et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents
Brian C. Geyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Chromatographic preparation and kinetic analysis of interactions between tabun enantiomers and acetylcholinesterase
O. Tenberken et al.
TOXICOLOGY LETTERS (2010)
Dramatic Differences in Organophosphorus Hydrolase Activity between Human and Chimeric Recombinant Mammalian Paraoxonase-1 Enzymes
Tamara C. Otto et al.
BIOCHEMISTRY (2009)
Functional Annotation and Three-Dimensional Structure of Dr0930 from Deinococcus radiodurans, a Close Relative of Phosphotriesterase in the Amidohydrolase Superfamily
Dao Feng Xiang et al.
BIOCHEMISTRY (2009)
Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase
Eugenie Carletti et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2009)
Reversed Enantioselectivity of Diisopropyl Fluorophosphatase against Organophosphorus Nerve Agents by Rational Design
Marco Melzer et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters
Patrick Masson et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2008)
Entry of oximes into the brain: A review
D. E. Lorke et al.
CURRENT MEDICINAL CHEMISTRY (2008)
A gas chromatographic-mass spectrometric approach to examining stereoselective interaction of human serum proteins with soman
David T. Yeung et al.
JOURNAL OF ANALYTICAL TOXICOLOGY (2008)
Engineered recombinant human paraoxonase 1 (rHuPON1) purified from Escherichia coli protects against organophosphate poisoning
Richard C. Stevens et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities
T. E. Reeves et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2008)
Effect of site-directed PEGylation of trichosanthin on its biological activity, immunogenicity, and pharmacokinetics
Qunxing An et al.
BIOMOLECULAR ENGINEERING (2007)
Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review
David E. Lenz et al.
TOXICOLOGY (2007)
Human paraoxonase:: A promising approach for pre-treatment and therapy of organophosphorus poisoning
Daniel Rochu et al.
TOXICOLOGY (2007)
PEGylated proteins: Evaluation of their safety in the absence of definitive metabolism studies
Rob Webster et al.
DRUG METABOLISM AND DISPOSITION (2007)
Enzyme-based intravascular defense against organophosphorus neurotoxins: Synergism of dendritic-enzyme complexes with 2-PAM and atropine
I. Petrikovics et al.
NANOTOXICOLOGY (2007)
The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase
Livnat Afriat et al.
BIOCHEMISTRY (2006)
Enzyme promiscuity: evolutionary and mechanistic aspects
Olga Khersonsky et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2006)
Microbial degradation of organophosphorus compounds
BK Singh et al.
FEMS MICROBIOLOGY REVIEWS (2006)
Effect of octanol : water partition coefficients of organophosphorus compounds on biodistribution and percutaneous toxicity
Steven E. Czerwinski et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2006)
Crystal structure of methyl parathion hydrolase from Pseudomonas sp WBC-3
YJ Dong et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily
C Roodveldt et al.
BIOCHEMISTRY (2005)
Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology
I Silman et al.
CURRENT OPINION IN PHARMACOLOGY (2005)
Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates
DT Yeung et al.
FEBS JOURNAL (2005)
Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state
C Roodveldt et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2005)
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes
M Harel et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Structure of the prolidase from Pyrococcus furiosus
MJ Maher et al.
BIOCHEMISTRY (2004)
Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon
I Petrikovics et al.
TOXICOLOGICAL SCIENCES (2004)
Minimizing the immunogenicity of protein therapeutics
AJ Chirino et al.
DRUG DISCOVERY TODAY (2004)
Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization
A Aharoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes
F Worek et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase:: temperature- and pH-dependence
D Rochu et al.
BIOCHEMICAL JOURNAL (2004)
Toxicokinetics of the nerve agent (±)-VX in anesthetized and atropinized hairless guinea pigs and marmosets after intravenous and percutaneous administration
MJ van der Schans et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site
CM Hill et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Neurobiology of butyrylcholinesterase
S Darvesh et al.
NATURE REVIEWS NEUROSCIENCE (2003)
Identification of an opd (organophosphate degradation) gene in an Agrobacterium isolate
I Horne et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2002)
Crystal structure of diisopropylfluorophosphatase from Loligo vulgaris
EI Scharff et al.
STRUCTURE (2001)
Enhancement, relaxation, and reversal of the stereoselectivity for phosphotriesterase by rational evolution of active site residues
M Chen-Goodspeed et al.
BIOCHEMISTRY (2001)
High-yield expression, purification, and characterization of the recombinant diisopropylfluorophosphatase from Loligo vulgaris
J Hartleib et al.
PROTEIN EXPRESSION AND PURIFICATION (2001)
Crystallization and preliminary X-ray crystallographic analysis of DFPase from Loligo vulgaris
EI Scharff et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2001)
Substrate and stereochemical specificity of the organophosphorus acid anhydrolase from Alteromonas sp JD6.5 toward p-nitrophenyl phosphotriesters
CM Hill et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2000)
Long ciuculating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism
I Petrikovics et al.
TOXICOLOGICAL SCIENCES (2000)