期刊
DRUG TESTING AND ANALYSIS
卷 4, 期 3-4, 页码 242-245出版社
WILEY-BLACKWELL
DOI: 10.1002/dta.344
关键词
Orbitrap; Q-Exactive; triple-TOF; IMS-MS(; MS); FT-ICR
Fast and unequivocal drug detection is of considerable importance in numerous fields of analytical chemistry, and today mass spectrometry-based approaches are often the method of choice due to their sensitive and specific nature. Mass spectrometry is in constant flux with innovations and thus supports the development of new, complementary assays for rapid determination of drugs and toxins as well as their metabolic products in clinical, forensic, and doping control laboratories. Examples of such innovations that have greatly aided the worldwide bioanalytical efforts are the modern improvements in ion trap, for example, Fourier transform-ion cyclotron resonance (FT-ICR) mass spectrometer - Orbitrap, and time-of-flight (TOF) mass analyzers when coupled with sensitive ionization techniques such as electrospray ionization. In this perspective, the utility of state-of-the-art mass spectrometers and recent instrumental developments such as new and/or improved hybrid analyzers are discussed and selected applications presented. Copyright (C) 2012 John Wiley & Sons, Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据