相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Population pharmacokinetic and pharmacodynamic analysis in allergic diseases
Mark Lovern et al.
DRUG METABOLISM REVIEWS (2009)
Pharmacokinetic variability of extended interval tobramycin in burn patients
David Bracco et al.
BURNS (2008)
Pharmacoecology: A new name for an old science
C. Flexner
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Gender differences in inflammatory proteins and pathways in seasonal allergic rhinitis
Fredrik Barrenas et al.
CYTOKINE (2008)
CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction
Ksenia Goryachkina et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Drug-induced long QT syndrome in women: Review of current evidence and remaining gaps
Raymond Hreiche et al.
GENDER MEDICINE (2008)
Sex, race, and smoking impact olanzapine exposure
Kristin L. Bigos et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia
Kosuke Doki et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2007)
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
Constanze Hilgendorf et al.
DRUG METABOLISM AND DISPOSITION (2007)
Disposition of desloratadine in healthy volunteers
R. Ramanathan et al.
XENOBIOTICA (2007)
Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers:: A single-dose, randomized, open-label, two-way crossover study
Anna Solans et al.
CLINICAL THERAPEUTICS (2007)
Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein
Tanja Obradovic et al.
PHARMACEUTICAL RESEARCH (2007)
Interrelationships of quantitative asthma-related phenotypes in the Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy
Marie-Pierre Oryszczyn et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Desloratadine for chronic idiopathic urticaria - A review of clinical efficacy
Lawrence DuBuske
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2007)
Clinical pharmacokinetic monitoring of midazolam in critically ill patients
Sean P. Spina et al.
PHARMACOTHERAPY (2007)
Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia
Junji Saruwatari et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Different gender response to serotonergic and noradrenergic antidepressants. A comparative study of the efficacy of citalopram and reboxetine
Carlos Berlanga et al.
JOURNAL OF AFFECTIVE DISORDERS (2006)
Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy
Ichiro Ieiri et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)
The effect of gender on the pharmacokinetics of verapamil and norverapamil in human
S. Dadashzadeh et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2006)
Differences in decline in GFR with age between males and females. Reference data on clearances of inulin and PAH in potential kidney donors
Ulla B. Berg
NEPHROLOGY DIALYSIS TRANSPLANTATION (2006)
The effect of CYP2J2, CYP3A4, CYP3A5 and the MDR1C3435T polymorphisms and gender on the urinary excretion of the metabolites of the H1-receptor antihistamine ebastine:: a pilot study
Guillermo Gervasini et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2006)
Gender-related differences in expression and function of hepatic P-glycoprotein and multidrug resistance-associated protein (Mrp2) in rats
Tatsuya Suzuki et al.
LIFE SCIENCES (2006)
Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate
R Ohashi et al.
DRUG METABOLISM AND DISPOSITION (2006)
Marked intraindividual variability in antiretroviral concentrations may limit the utility of therapeutic drug monitoring
RE Nettles et al.
CLINICAL INFECTIOUS DISEASES (2006)
Clinical implications of CYP3A polymorphisms
Leszek Wojnowski et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2006)
Anti-inflammatory - Adult and paediatric poor metabolisers of desloratadine: an assessment of pharmacokinetics and safety
Bruce Prenner et al.
EXPERT OPINION ON DRUG SAFETY (2006)
Sex differences in the mRNA, protein, and functional expression of organic anion transporter (Oat) 1, Oat3, and organic cation transporter (Oct) 2 in rabbit renal proximal tubules
CE Groves et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Gender differences in p-glycoprotein:: Drug toxicity and response
M Davis
JOURNAL OF CLINICAL ONCOLOGY (2005)
Effect of CYP2D6*10 allele on the pharmacokinetics of loratadine in Chinese subjects
OQP Yin et al.
DRUG METABOLISM AND DISPOSITION (2005)
CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele
SC Sim et al.
PHARMACOGENETICS AND GENOMICS (2005)
A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis
G Passalacqua et al.
CLINICAL THERAPEUTICS (2005)
Pharmacokinetic variability of anticancer agents
SD Undevia et al.
NATURE REVIEWS CANCER (2005)
Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)
M Niemi et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Do men and women differ in proximal small intestinal CYP3A or P-glycoprotein expression?
MF Paine et al.
DRUG METABOLISM AND DISPOSITION (2005)
Contribution to variability in response to opioids
G Hanks et al.
SUPPORTIVE CARE IN CANCER (2005)
Whole-genome patterns of common DNA variation in three human populations
DA Hinds et al.
SCIENCE (2005)
Sex and racial differences in pharmacological response: Where is the evidence? Pharmacogenetics, pharmacokinetics, and pharmacodynamics
GD Anderson
JOURNAL OF WOMENS HEALTH (2005)
In vitro partition of irinotecan (CPT-11) in human volunteer blood: the influence of concentration, gender and smoking
H Dumez et al.
ANTI-CANCER DRUGS (2005)
Population pharmacokinetics of epinastine, a histamine H-1 receptor antagonist, in adults and children
A Sarashina et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Tacrolimus pharmacokinetics in lung transplantation: New strategies for monitoring
R Ragette et al.
JOURNAL OF HEART AND LUNG TRANSPLANTATION (2005)
Influx and efflux transport of H1-antagonist epinastine across the blood-brain barrier
N Ishiguro et al.
DRUG METABOLISM AND DISPOSITION (2004)
Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic
JC Verster et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2004)
Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6
TT Denton et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Prevalence of the slow metabolizer (SM) phenotype and single dose pharmacokinetics (PK) of desloratadine (DCL) in a population of healthy adults.
GS Frick et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
The effects of gender, age, ethnicity, and liver cirrhosis on cytochrome P450 enzyme activity in human liver microsomes and inducibility in cultured human hepatocytes
A Parkinson et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans
M Molimard et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2004)
MDR-1 C3435T polymorphism influences cyclosporine A dose requirement in liver-transplant recipients
L Bonhomme-Faivre et al.
TRANSPLANTATION (2004)
P-glycoprotein (P-gp/MDR1)-mediated efflux of sex-steroid hormones and modulation of P-gp expression in vitro
WY Kim et al.
PHARMACEUTICAL RESEARCH (2004)
A variant 2677A allele of the MDR1 gene affects fexofenadine disposition
SY Yi et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2004)
CYP3A4 polymorphisms -: Potential risk factors for breast and prostate cancer:: A HuGE review
C Keshava et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2004)
Pharmacokinetics and safety of ebastine in patients with impaired hepatic function compared with healthy volunteers - A phase I open-label study
KC Lasseter et al.
CLINICAL PHARMACOKINETICS (2004)
Steady-state brain concentrations of antihistamines in rats - Interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding
KMM Doan et al.
PHARMACOLOGY (2004)
Comparative molecular field analysis and QSAR on substrates binding to cytochrome P450 2D6
S Haji-Momenian et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2003)
Sex differences in the toxicokinetics of inhaled solvent vapors in humans -: 2.: 2-propanol
L Ernstgård et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
Med-psych drug-drug interactions update - Antihistamines
SC Armstrong et al.
PSYCHOSOMATICS (2003)
The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity
JC Gorski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)
The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients
CR Yates et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2003)
Classic histamine H1 receptor antagonists:: A critical review of their metabolic and pharmacokinetic fate from a bird's eye view
A Sharma et al.
CURRENT DRUG METABOLISM (2003)
Impact of interpatient pharmacokinetic variability on design considerations for therapy with radiolabeled MAbs
G DeNardo et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2003)
Gender differences in drug effects: implications for anesthesiologists
H Pleym et al.
ACTA ANAESTHESIOLOGICA SCANDINAVICA (2003)
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients
B Chowbay et al.
PHARMACOGENETICS (2003)
Drug transport proteins in the liver
KN Faber et al.
ADVANCED DRUG DELIVERY REVIEWS (2003)
Modeling of intestinal drug absorption: Roles of transporters and metabolic enzymes (for the Gillette Review Series)
KS Pang
DRUG METABOLISM AND DISPOSITION (2003)
The influence of sex on pharmacokinetics
JB Schwartz
CLINICAL PHARMACOKINETICS (2003)
MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males
T Gerloff et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2002)
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs
KMM Doan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Genetic contribution to variable human CYP3A-mediated metabolism
JK Lamba et al.
ADVANCED DRUG DELIVERY REVIEWS (2002)
Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene
A Johne et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Growth hormone secretion pattern is an independent regulator of growth hormone actions in humans
CA Jaffe et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA
I Koch et al.
DRUG METABOLISM AND DISPOSITION (2002)
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
K Tang et al.
PHARMACOGENETICS (2002)
Association of the P-glycoprotein transporter MDR1C3435T polymorphism with the susceptibility to renal epithelial tumors
M Siegsmund et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects
DI Min et al.
THERAPEUTIC DRUG MONITORING (2002)
Gender difference in the Oatp1-mediated tubular reabsorption of estradiol 17β-D-glucuronide in rats
Y Gotoh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2002)
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
S Drescher et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2002)
Effects of emedastine and cetirizine, alone and with alcohol,on actual driving of males and females
A Vermeeren et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2002)
Involvement of CYP2J2 and CYP4F12 in the metabolism of ebastine in human intestinal Microsomes
T Hashizume et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Now important are gender differences in pharmacokinetics?
B Meibohm et al.
CLINICAL PHARMACOKINETICS (2002)
Pharmacokinetic profile of zafirlukast
PNR Dekhuijzen et al.
CLINICAL PHARMACOKINETICS (2002)
Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
JK Lamba et al.
PHARMACOGENETICS (2002)
The genetic determinants of the CYP3A5 polymorphism
E Hustert et al.
PHARMACOGENETICS (2001)
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
J Zhang et al.
PHARMACOGENETICS (2001)
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
T Sakaeda et al.
PHARMACEUTICAL RESEARCH (2001)
Role of transport proteins in drug absorption, distribution and excretion
A Ayrton et al.
XENOBIOTICA (2001)
Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers
E Baltes et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2001)
Identification of functionally variant MDR1 alleles among European Americans and African Americans
RB Kim et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2001)
Lack of gender differences and large intrasubject variability in cytochrome P450 activity measured by phenotyping with dextromethorphan
JS McCune et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2001)
Identification and functional characterization of eight CYP3A4 protein variants
R Eiselt et al.
PHARMACOGENETICS (2001)
Population pharmacokinetic analysis and optimization of the experimental design for mizolastine solution in children
F Mentré et al.
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2001)
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
P Kuehl et al.
NATURE GENETICS (2001)
Smoking in patients receiving psychotropic medications - A pharmacokinetic perspective
HD Desai et al.
CNS DRUGS (2001)
Is gender a risk factor for adverse drug reactions? The example of drug-induced long QT syndrome
MD Drici et al.
DRUG SAFETY (2001)
Race and sex influence clearance of nifedipine: Results of a population study
ME Krecic-Shepard et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)
Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates
L Labbé et al.
PHARMACOGENETICS (2000)
Clinical pharmacokinetics of mirtazapine
CJ Timmer et al.
CLINICAL PHARMACOKINETICS (2000)
Functional polymorphisms of the human multidrug-resistance gene:: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
S Hoffmeyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity
F Sata et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)
Drug-grapefruit juice interactions
GC Kane et al.
MAYO CLINIC PROCEEDINGS (2000)