期刊
DRUG DISCOVERY TODAY
卷 18, 期 3-4, 页码 155-162出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2012.09.001
关键词
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资金
- Natural Science Foundation of China [30600663, 81071018, 81171189]
- Pujiang Talents at Shanghai [10PJ1401700]
- Science and Technology Commission of Shanghai Municipality [09411960900]
- Shanghai Municipal Health Bureau [2010-155]
- NIH [T32 ES007032, R01-AG033398, P42-ES004696, 5897, P30-ES007033, 6364, R01-ES016873, R01-ES019277, R01-NS057567, P50-NS062684, 6221]
- NIEHS [T32 ES015459]
- MJFF
This review summarizes major advances in biomarker discovery for diagnosis, differential diagnosis and progression of Parkinson's disease (PD), with emphasis on neuroimaging and biochemical markers. Potential strategies to develop biomarkers capable of predicting PD in the prodromal stage before the appearance of motor symptoms or correlating with nonmotor symptoms, an active area of research, are also discussed.
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