期刊
DRUG DISCOVERY TODAY
卷 18, 期 3-4, 页码 128-140出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2012.08.002
关键词
-
资金
- National Institutes of Health [RO1 CA138791, U54 CA163120, EDRN UO1 CA111294]
- U.S. Department of Defense [PC074289]
The in vivo zebrafish models have recently attracted great attention in molecular oncology to investigate multiple genetic alterations associated with the development of human cancers and validate novel anticancer drug targets. Particularly, the transparent zebrafish models can be used as a xenotransplantation system to rapidly assess the tumorigenicity and metastatic behavior of cancer stem and/or progenitor cells and their progenies. Moreover, the zebrafish models have emerged as powerful tools for an in vivo testing of novel anticancer agents and nanomaterials for counteracting tumor formation and metastases and improving the efficacy of current radiation and chemotherapeutic treatments against aggressive, metastatic and lethal cancers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据