期刊
DRUG DISCOVERY TODAY
卷 17, 期 21-22, 页码 1160-1165出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2012.06.009
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资金
- NICHD NIH HHS [P50 HD044405] Funding Source: Medline
The development of biologic molecules (monoclonal antibodies, cytokines, soluble receptors) as specific therapeutics for human disease creates a need for animal models in which safety and efficacy can be tested. Models in lower animal species are precluded when the reagents fail to recognize their targets, which is often the case in rats and mice. In this Feature article we will highlight the common marmoset, a small-bodied nonhuman primate (NHP), as a useful model in biomedical and preclinical translational research.
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