期刊
DRUG DISCOVERY TODAY
卷 15, 期 13-14, 页码 547-552出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2010.05.003
关键词
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A short review is proposed on the existing literature for the research performed in calcium phosphate (CaP) biomaterials used as drug delivery systems. In the first part, a brief update is given on the performance of both CaP ceramics and CaP cements. Second, a review of the research and clinical situation is developed for CaP materials already used as drug delivery systems. Experimental works performed for local delivery are reported. In particular, a description is given of the in vitro and in vivo studies in which these materials are loaded with various proteins and drugs.
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