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Delivery of anti-angiogenic molecular therapies for retinal disease

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DRUG DISCOVERY TODAY
卷 15, 期 7-8, 页码 272-282

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ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2010.02.004

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Angiogenic diseases of the retina are the leading cause of blindness in the developed world. The development of anti-angiogenic molecular therapies has transformed the prognosis of these conditions, especially age-related macular degeneration. With these new treatments comes the new challenge of delivering an effective dosage to the retina, over a prolonged period of time and in a safe and cost-effective manner. A range of new anti-angiogenics are on the horizon, offering new and varied modes of drug delivery. In addition, a range of new sustained-release drug delivery technologies are being developed.

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