期刊
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
卷 145, 期 -, 页码 25-29出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jphotobiol.2015.02.007
关键词
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资金
- endMS Summer Research Studentship
- Multiple Sclerosis Society of Canada Doctoral Studentship
- Early Research Award from the Government of Ontario
- Natural Sciences and Engineering Research Council of Canada
- Hospital for Sick Children Restracomp Fellowship
Query of sun-related habits or ancestry could help screen for risk of vitamin D insufficiency (serum 25-hydroxyvitamin D < 75 nmol/L). We evaluated the association between Sun Exposure Score (calculated from recall of Time Exposed to Sun and Skin Exposed to Sun in the previous week), demographics and anthropometrics (including self-reported ancestry and skin melanin reflectometry), and serum 25(OH)D levels in healthy young Canadian adults in the Greater Toronto Area (GTA; 43 N) during fall. 310 adults (67% female) of European, East Asian, and South Asian ancestries were evaluated. The median (interquaitile range) 25(OH)D level was 49.7 nmol/L (36.7-70.3) and 80% of participants were vitamin D insufficient. The vast majority of those of East and South Asian ancestry were vitamin D insufficient (91% and 97%, respectively), as were 55% of those of European ancestry. Sun Exposure Score and 25(OH)D concentrations were not associated after accounting for confounders. A multivariable model showed ancestry, recent summer sun exposure, sex, melanin, vitamin D intake, age and year of study significantly predicted 25(OH)D concentration; ancestry was the strongest independent predictor (adjusted R-2 = 43%). Although Sun Exposure Score was not a significant predictor of serum 25(OH)D levels, inquiry of ancestry has potential use in screening for vitamin D insufficiency. (C) 2015 Elsevier B.V. All rights reserved.
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