期刊
DNA REPAIR
卷 9, 期 12, 页码 1256-1263出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dnarep.2010.09.018
关键词
DNA repair; DNA double strand breaks; Non-homologous end-joining; Homologous recombination
The repair of DNA double strand breaks (dsb) is important for maintaining the physical and genetic integrity of the genome. Moreover, in humans it is associated with the prevention of diseases such as immune deficiencies and cancer. This review briefly explores the fundamental strategies for repairing dsb, examines how cells maximize the fidelity of dsb repair in the cell cycle and discusses the requirements for dsb repair in the context of chromatin. (C) 2010 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据