期刊
DISSOLUTION TECHNOLOGIES
卷 19, 期 1, 页码 6-11出版社
DISSOLUTION TECHNOLOGIES, INC
DOI: 10.14227/DT190112P6
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资金
- Pharmaceutical Faculty, Jagiellonian University Medical College [K/ZBW/000219]
Because drug quality is the focus for pharmaceutical industry and regulatory agencies, the in vitro dissolution test becomes a standard tool for characterization of manufactured products. However, results of the dissolution test must be expressed in mathematical terms; this is realized by fitting various models to the cumulative dissolution curves. The models might be either mechanistic or empirical. The fitting process requires software (e.g., KinetDS) for automation and determination of possible release mechanisms of drug substances from the dosage forms. The software is FOSS (Free Open Source Software) and is available at http://sourceforge.net/projects/kinetds/.
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