期刊
DISEASES OF THE COLON & RECTUM
卷 52, 期 6, 页码 1072-1079出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1007/DCR.0b013e31819ef79a
关键词
Diverticular colitis; Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Segmental colitis; Crescenteric colitis
资金
- John and Caroline Price Trust
PURPOSE: Diverticular-associated colitis significantly overlaps clinically with primary inflammatory bowel disease. However, the clinical and the pathologic features of diverticular-associated colitis suggest that it is a distinct clinical entity. METHODS: We performed a systematic review by use of multiple health care databases and gray literature, following predefined inclusion and exclusion criteria to determine the clinical, endoscopic, and pathologic features of diverticular-associated colitis, and recurrence rates following medical and surgical treatment. RESULTS: Two hundred twenty-seven participants were selected from 18 eligible studies, including our own patients (n = 13). The average age of disease onset was 64 years. The typical symptoms included tenesmus, hematochezia, and diarrhea. One hundred sixty-three of the 227 patients in these studies were classified as having diverticular-associated colitis, of which 142 were managed medically. Twenty-eight patients eventually required an operation. One-quarter (37 of 163) of the patients had recurrence of symptoms with an average follow-up time of three years. CONCLUSIONS: Diverticular-associated colitis is a distinct entity that presents with segmental colitis and a variety of clinical, endoscopic, and pathologic features. Diverticular-associated colitis should be considered in the presence of recurrent symptoms after resection for diverticulitis.
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