期刊
DISEASES OF THE COLON & RECTUM
卷 51, 期 3, 页码 306-311出版社
SPRINGER
DOI: 10.1007/s10350-007-9173-4
关键词
obstruction; left-sided colorectal cancer; primary resection; delayed resection
Purpose: By comparing surgical outcomes between primary and delayed resection, we addressed whether and how surgical strategies impacted prognosis of patients with left-sided colorectal cancer underwent emergency curative resection. Methods: Between January 1980 and December 2002, a total of 143 patients were identified who presented with obstructive left-sided colorectal cancer and received emergency curative resection in Taipei Veterans General Hospital. Patients were stratified according to the timing of tumor resection into two groups: primary resection and delayed resection. Demographic data of the patients, characteristics of the tumors, and short-term and long-term outcomes were analyzed and compared between the two groups. Conclusions: The demographic data and tumor characteristics did not differ between the two groups except for more rectal cancers in the delayed resection group (P = 0.021). Primary resection group had a higher anastomotic leakage rate (P = 0.017) and a trend toward a higher mortality rate, which did not reach statistical significance (P = 0.063). The median follow-up intervals were similar (60.4 vs. 58.3 months; P = 0.79). The median survival tended to be longer in delayed resection group (66 vs. 105 months; P = 0.088). Overall five-year and ten-year survival for primary resection were 43.7 and 31.9 percent, respectively, compared with 67.2 and 53.2 percent, respectively, for delayed resection. Conclusions: Delayed resection seems to be a safer procedure and provided a better oncologic outcome compared with primary resection in obstructive left-sided colorectal cancer under emergency situations.
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