期刊
DISABILITY AND REHABILITATION
卷 37, 期 21, 页码 1940-1945出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/09638288.2014.991451
关键词
Bronchopulmonary dysplasia; executive functioning; health-related quality of life; social functioning; very-low birth weight
资金
- Research Forum for the Child, Queen's University Belfast
- Friends of Jessica Trust
- Northern Ireland Chest, Heart and Stroke Association
- Perinatal Trust Fund, Royal Victoria Hospital
Purpose: To assess long-term impairments of executive functioning in adult survivors of bronchopulmonary dysplasia (BPD). Method: Participants were assessed on measures of executive functioning, health-related quality of life (HRQoL) and social functioning. Survivors of BPD (n = 63; 34 males; mean age 24.2 years) were compared with groups comprising preterm (without BPD) (<1500 g; n = 45) and full-term controls (n = 63). Analysis of variance was used to explore differences among groups for outcome measures. Multiple regression analyzes were performed to identify factors predictive of long-term outcomes. Results: Significantly more BPD adults, compared with preterm and term controls, showed deficits in executive functioning relating to problem solving (OR: 5.1, CI: 1.4-19.3), awareness of behavior (OR: 12.7, CI: 1.5-106.4) and organization of their environment (OR: 13.0, CI: 1.6-107.1). Birth weight, HRQoL and social functioning were predictive of deficits in executive functioning. Conclusions: This study represents the largest sample of survivors into adulthood of BPD and is the first to show that deficits in executive functioning persist. Children with BPD should be assessed to identify cognitive impairments and allow early intervention aimed at ameliorating their effects.
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