期刊
DIGESTIVE DISEASES AND SCIENCES
卷 53, 期 9, 页码 2318-2329出版社
SPRINGER
DOI: 10.1007/s10620-008-0415-7
关键词
gastroesophageal reflux disease; obesity; bariatric surgery; Roux-en-Y; gastric bypass
资金
- Eisai, Inc
- PriCara
- Ortho-McNeil, Inc
- International Meetings and Science, Inc
Bariatric surgery is ubiquitous today. In the obese patient with comorbid gastroesophageal reflux disease (GERD), it is increasingly being used as an alternative to fundoplication because it not only has an effect on GERD but also on other comorbid illnesses. Traditional GERD surgery is designed to augment the mechanical barriers against reflux, decrease acid production in the stomach, improve gastric emptying, or divert bile from the stomach. Roux-en-Y gastric bypass addresses these issues in addition to resulting in profound weight loss in patients. Banding may have a positive influence in patients' GERD, though to a lesser extent. The duodenal switch provides excellent control for patients with alkaline reflux. A revision of the 1991 National Institutes of Health guidelines for determining bariatric surgical candidates is overdue, and it may be feasible to consider expanding the body mass index and comorbidity requirements to reflect the benefits offered by these techniques for GERD patients.
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