期刊
DIGESTIVE DISEASES AND SCIENCES
卷 54, 期 3, 页码 578-585出版社
SPRINGER
DOI: 10.1007/s10620-008-0399-3
关键词
Gastric pH; Bravo capsule; Slimline catheter; Gastric acid; Telemetry
资金
- Korea Health 21 R and D Project [A060093]
- Ministry of Health and Welfare, Republic of Korea
Purpose The delivery system of the Bravo capsule was designed for placement on the esophagus. We evaluated the feasibility of our novel placement method of the Bravo capsule using a clip to monitor intragastric pH and to compare the accuracy of the Bravo wireless system to the traditionally used Slimline catheter-Mark III Digitrapper pH monitoring system. Methods The Bravo capsule was placed by clip or conventional delivery system using suction on the gastric wall in 20 fasted subjects. A separate group of ten healthy volunteers underwent simultaneous intragastric pH monitoring for comparison of the two systems with meals. Results Early dislodgment rate of the capsules was lower when placed using clipping (20%) than using conventional delivery system (70%) within 48 h after placement. We observed prominent movement of one catheter in the stomach during the study. Post-test calibration drifts of the catheters at pH 7.01 were significantly greater than those of the Bravo capsules (P = 0.02). Conclusion Our novel clipping method of the Bravo pH capsule placement provided accurate monitoring of intragastric pH with merits of tolerability, acid stability, and fixing position.
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