期刊
DIGESTIVE AND LIVER DISEASE
卷 45, 期 7, 页码 558-561出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.dld.2012.11.004
关键词
Crohn's disease; Videocapsule endoscopy; Therapeutic management
资金
- Given Imaging
Background: The role of small bowel capsule endoscopy in the management of established Crohn's disease is uncertain. Methods: A retrospective study of small bowel capsule endoscopy tests performed in a referral centre from 2008 to 2011; 77 tests were performed in patients with known Crohn's disease. Six patients were excluded due to capsule test retention. Patients were classified into 4 indication groups: unexplained anaemia (G1, n = 6); discrepancy between clinical symptoms and morphology (G2, n = 25), full assessment of Crohn's disease location (G3, n = 37) and evaluation of mucosal healing (G4, n = 3). Results: Twenty-seven (38%) patients had no lesions, 32 (45%) moderate and 12 (17%) severe lesions. Endoscopic lesions were found in 4/6 (67%) G1 patients, 11/25 (44%) G2 and 28/37 (76%) G3 (p < 0.03). Three months after endoscopy was performed, 38/71 patients experienced a change in their treatment that was significantly associated with the severity of endoscopic lesions and with test indications; in 60%, 20% and 58% of patients from G1, G2 and G3, respectively (p < 0.01). Conclusion: Small bowel capsule endoscopy resulted in management changes in the majority of patients with established Crohn's disease. (c) 2012 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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