期刊
DIGESTIVE AND LIVER DISEASE
卷 41, 期 1, 页码 26-30出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.dld.2008.02.023
关键词
Endoscopic submucosal dissection; Piecemeal resection; Snaring resection; Stomach neoplasm
Background. Endoscopic submucosal dissection (ESD) is a novel endolunninal technique that permits the resection of gastric neoplasms. Aim. To analyse the feasibility of snaring as the final step of ESD. Patients and methods. One hundred and ninety-nine consecutive gastric neoplasms resected by four ESD experts from January 2004 to May 2007 were investigated. Forty-five (22.6%) were finally resected finally using a snare. Rates of en bloc resection, complete (R0 plus ell bloc) resection, mean operation time, and complications were assessed between the snaring and the non-snaring groups. Results. En bloc resection rate was significantly lower and delayed bleeding rate was significantly higher in the snaring group than in the non-snaring group (91.1% [41/45] vs. 100% [154/154], 11.1% [5/45] vs. 1.9% [3/154], respectively), although complete resection rate (86.7% [39/45] vs. 92.9% [143/154]) and mean operation time (70.2 min vs. 75.8 min) were not significantly different between the two groups. Six perforation cases (3 [6.7%] in the snaring group, 3 [1.9%] in the non-snaring group) were observed, but snaring did not lead to perforation in any case. When the subjects were divided into small (<= 2 cm) and large (>2 cm) tumours, en bloc resection rate in large tumours was still significantly different between the groups (76.9% [10/13] vs. 100% [67/67]), whereas in small tumours it was no longer significantly different (96.9% [31/32] vs. 100% [87/87]). Conclusions. Snaring may facilitate successful ESD for smaller tumours, but multiple-piece resection should be taken into account especially for larger tumours. (C) 2008 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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